EPIGENETIC MARK CONFIRMED IN MAMMALS
Researchers from Yale University confirmed there is a new epigenetic mark, adenine methylation (N6-methyladenine), in mouse stem cells; researchers in the U.K. say that this same mark may also be in adult human cell’s DNA. They say it was found “six or seven times for every one million adenine bases.” This epigenetic mark has been found in bacterial genomes, worms, and plants, but this is the first evidence of it being found in mammals. Adenine methylation was ignored, in DNA, for a while, but now this new evidence has brought up more questions. The same Yale researchers also found the enzyme (Alkbh1) that removed N6-methyladenine.
The entire article, published by the-scientist.com, can be found here: http://www.the-scientist.com/?articles.view/articleNo/45710/title/New-Epigenetic-Mark-Confirmed-in-Mammals/
More info can be found here: http://cen.acs.org/articles/94/i14/New-epigenetic-mark-found-mammalian.html?type=paidArticleContent
and here: http://www.nature.com/nature/journal/v532/n7599/full/nature17640.html
Author: Naomi Chernowski
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