Recently scientists have discovered activity of a gene that may affect the enzyme (CYP1A2) that handles the breakdown of coffee during metabolism. Basically, the more of this gene you have, the less likely you are to have a craving of caffeine. This gene is called PDSS2. Scientists tested the fact that it eliminates enzyme CYP1A2 by selecting a group of Italian and Dutch people. Italians drink around 2 cups of espresso a day and the Dutch about 5 filtered cups, both on average. Scientists tested both of their genetic make-ups and found much less PDSS2 in the Italians. However with all the different variables contributing in this experiment from nationality to cup size, scientists concluded that other genes, such as CYP1A2 controls high amounts of caffeine intake while the lovely PDSS2 controls smaller intake amounts.
View the full article here: https://www.sciencenews.org/article/thank-or-blame-your-genes-ability-handle-java-jolt?mode=topic&context=87&tgt=nr
Author: Jack Casey
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